Research & Resources
The following compilation of resources and disease/condition specific research is by no means comprehensive, but we hope it provides some insight into the broad application of hyperbaric oxygen therapy and its possible benefits.
General Resources
- Hyperbaric Medicine: A Brief History
Hyperbaric Medicine (Wikipedia) - Application of medical gases in the field of neurobiology
- FDA Issues Deceptive Statement about HBOT (Hyperbaric Oxygen Therapy) (Press Release-September 10, 2013)
- Hyperbaric Oxygen Therapy – Why the Controversy? Pt 1/3 (video)
- Hyperbaric Oxygen Therapy – Why the Controversy? Pt 2/3 (video)
- Hyperbaric Oxygen Therapy – Why the Controversy? Pt 3/3 (video)
- Hyperbaric oxygen and wound healing (An article summarizing mechanisms of action and general application of HBOT)
- Hyperbaric oxygen therapy promotes neurogenesis: where do we stand? (An article addressing autologous neurogenesis and cellular transcription)
- Hyperbaric Medical Solutions News 12 Segment (video)
- Hyperbaric Oxygen Therapy for Wounds
- All the right moves: the need for the timely use of hyperbaric oxygen therapy for treating TBI/CTE/PTSD
- SEVEN DAYS ARTICLE MAY 31 2017
Acute Severe Problems From Accidents (i.e. Crushed Leg, Arm, Fingers)
- Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy.
- Case Report: Successful Treatment Of Acute Exertional Paraspinal Compartment Syndrome With Hyperbaric Oxygen Therapy
- The effect of hyperbaric oxygen in crush injuries and skeletal muscle-compartment syndromes (abstract)
- Effects of hyperbaric oxygen therapy on facial nerve regeneration (abstract)
- Fasciotomy closure using simultaneous vacuum-assisted closure and hyperbaric oxygen (abstract)
- Treatment of open fractures and crush injuries (abstract)
- Severe lower limb crush injury and the role of hyperbaric oxygen treatment: a case report. (abstract)
- Hyperbaric Oxygen Treatment for Reflex Sympathetic Dystrophy Syndrome RSD (video)
Anemia
- The effect of hyperbaric oxygen on severe anemia (abstract)
- A systematic review of the application of hyperbaric oxygen in the treatment of severe anemia: an evidence-based approach (abstract)
Arthritis-Rheumatoid, Osteoarthritis & Osteoarthrosis
- Hyperbaric Oxygen Treatments for Rheumatoid Arthritis (pdf)
- Effects of exposure to hyperbaric oxygen on oxidative stress in rats with type II collagen-induced arthritis (abstract)
- Hyperbaric oxygenation in the comprehensive therapy of patients with rheumatoid arthritis (clinico-immunologic study (abstract)
- Radiation-modifying effect of oxygen barotherapy in complex treatment of patients with rheumatoid arthritis and osteoarthrosis (abstract)
- Pain improvement in rheumatoid arthritis with hyperbaric oxygen: report of three cases
- Oxygen Oasis Center for Healing: Rheumatoid Arthritis
- Hyperbaric Oxygen therapy helps Osteoarthritis and degenerative joint/cartilage disease (article)
- Pain improvement in rheumatoid arthritis with hyperbaric oxygen: report of three cases
- New, targeted therapies in RA provide hope for people with this condition
Athletic Injuries & Performance
- Hyperbaric Oxygen Effects on Sports Injuries
- Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports
- Hyperbaric oxygen as an adjuvant for athletes (abstract)
- Hyperbaric Therapy for Sports Recovery (abstract)
- Darren Sharper’s Hyperbaric Chamber (video)
- Hyperbarics for Sports Recovery
- Early Recovery of Exercise-Related Muscular Injury by HBOT. – PubMed – NCBI
Autism, Down Syndrome
- Hyperbaric oxygen treatment in autism spectrum disorders
- How hyperbaric oxygen therapy helped my daughter with down syndrome
- Children With Autism and Hyperbaric Oxygen Chamber Studies Part 1 (video)
- HBOT for Autism (video)
- CTV News clip – Hyperbaric Oxygen Therapy (HBOT) and Autism at Under Pressure Inc. (video)
- Hyperbaric Oxygen Therapy Works (Autism) (video)
- Autism Therapy Success Stories in Minnesota using Hyperbaric Oxygen Therapy HBOT (video)
- Hyperbaric oxygen therapy in Thai autistic children
- The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study
- Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial
- Care: The Center for Autism and Education
- The Autism Community in Action (TACA)
- Hyperbaric oxygen therapy might improve certain pathophysiological findings in autism (abstract)
- How mild hyperbaric oxygen therapy works and why it is good for our children (pdf)
- Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?
- Brief report: Hyperbaric oxygen therapy (HBOT) in children with autism spectrum disorder: a clinical trial (abstract)
- Hyperbaric Oxygen Treatments for Autistic Children (video)
- Therapeutic use of hyperbaric oxygen therapy for children with autism spectrum disorder.
- Hyperbaric Oxygen Therapy and Autism (video)
Autoimmune Disorders/Lupus
- Suppressive effect of hyperbaric oxygenation on immune responses of normal and autoimmune mice
- Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy (abstract)
- Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with toxic injury due to mold exposure
- Hyperbaric oxygen and lymphoid system function: A review supporting possible intervention in tissue transplantation (abstract)
- Refractory vasculitic ulcer of the toe in adolescent suffering from Systemic Lupus Erythematosus treated successfully with hyperbaric oxygen therapy
- Allergy & Immunity – Wisconsin Hyperbarics – Myasthenia Gravis
Bone Disorders/Conditions/Pain
- Effect of hyperbaric oxygen on bone healing after enucleation of mandibular cysts: a modified case control study (abstract)
- There may be a role for hyperbaric oxygen therapy in transient osteoporosis of the hip (abstract)
- The influence of hyperbaric oxygen treatment on the healing of experimental defects filled with different bone graft substitutes
- Bone disease with pain. Osteomyelitis in the long bone (abstract)
Cancer & Cancer Treatment and Radiation Damage/Burns
- Efficacy of hyperbaric oxygen therapy combined with mild hyperthermia for improving the anti-tumour effects of carboplatin.
- Hyperbaric oxygen as an adjunctive therapy in treatment of malignancies, including brain tumours.
- Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy.
- Synergistic Inhibitory Effect of Hyperbaric Oxygen Combined with Sorafenib on Hepatoma Cells
- Effects of different doses of hyperbaric oxygen on cisplatin-induced nephrotoxicity.
- Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model.
- The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer
- Long-term experience of hyperbaric oxygen therapy for refractory radio- or chemotherapy-induced haemorrhagic cystitis
- Hyperbaric oxygen therapy for late radiation-induced tissue toxicity:outcome measures in breast cancer patients
- American Cancer Society
- Hyperbaric oxygen therapy and cancer—a review
- Effect of hyperbaric oxygen treatment on oxygen tension and vascular capacity in irradiated skin and mucosa (abstract)
- Dr. Paul Harch HBOT in Cancer Lecture (video)
- The efficacy of hyperbaric oxygen therapy in the treatment of radiation-induced late side effects
- Feasibility study of metabolically supported chemotherapy with weekly carboplatin/paclitaxel combined with ketogenic diet, hyperthermia and hyperbaric oxygen therapy in metastatic non-small cell lung cancer.
- Hyperbaric oxygen therapy for late radiation tissue injury (abstract)
- Hyperbaric oxygen therapy for radiation-induced cystitis and proctitis (abstract)
- Hyperbaric oxygen treatment in radiation-induced cystitis and proctitis: a prospective cohort study on patient-perceived quality of recovery (abstract)
- Issels Integrative Oncology
- The use of hyperbaric oxygen for treating delayed radiation injuries in gynecologic malignancies: a review of literature and report of radiation injury incidence (abstract)
- Hyperbaric oxygenation therapy alleviates chronic constrictive injury-induced neuropathic pain and reduces tumor necrosis factor-alpha production. (abstract)
- Hyperbaric oxygen treatment improved neurophysiologic performance in brain tumor patients after neurosurgery and radiotherapy: a preliminary report (abstract)
- Hyperbaric oxygenation for tumour sensitisation to radiotherapy (abstract)
- Hyperbaric oxygen therapy effectively treats long-term damage from radiation therapy (from UCLA Health)
- Early hyperbaric oxygen therapy for reducing radiotherapy side effects: early results of a randomized trial in oropharyngeal and nasopharyngeal cancer (abstract)
- Improved quality of life with hyperbaric oxygen therapy in patients with persistent pelvic radiation-induced toxicity (abstract)
- Does hyperbaric oxygen administration decrease side effect and improve quality of life after pelvic radiation? (abstract)
- The effect of hyperbaric oxygen therapy on quality of life in oral and oropharyngeal cancer patients treated with radiotherapy (abstract)
- Treatment of refractory radiation-induced hemorrhagic proctitis with hyperbaric oxygen therapy (abstract)
- Treatment of radiation proctitis with hyperbaric oxygen (abstract)
- Hyperbaric oxygen therapy for delayed radiation injuries in gynecological cancers (abstract)
- Hyperbaric oxygen: does it promote growth or recurrence of malignancy? (abstract)
- Does hyperbaric oxygen treatment have the potential to increase salivary flow rate and reduce xerostomia in previously irradiated head and neck cancer patients? A pilot study (abstract)
- The effect of hyperbaric oxygenation on postradiation xerostomia and saliva in patients with head and neck tumours (abstract)
- Hyperbaric oxygen therapy for late radiation tissue injury in gynecologic malignancies
- Hyperbaric oxygen therapy for treatment of adverse radiation effects after stereotactic radiosurgery of arteriovenous malformations: case report and review of literature (abstract)
- Hyperbaric oxygen in the treatment of a radiosurgical complication: technical case report (abstract)
- Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema after LINAC radiosurgery (abstract)
- Treatment of a radiation-induced rectal ulcer with hyperbaric oxygen therapy in a man with prostate cancer (abstract)
- Lung metastatic load limitation with hyperbaric oxygen (abstract)
- Hyperbaric oxygen and malignancies: a potential role in radiotherapy, chemotherapy, tumor surgery and phototherapy (abstract)
- The utility of hyperbaric oxygen therapy to treat recurrent acute bowel obstruction after previous pelvic radiotherapy: a case series (abstract)
- Potential roles of hyperbaric oxygenation in the treatments of brain tumors. (abstract)
- Effects of radiotherapy after hyperbaric oxygenation on malignant gliomas. (abstract)
- Can hyperbaric oxygenation decrease doxorubicin hepatotoxicity and improve regeneration in the injured liver?
- Stem Cell Collection And Hyperbaric Oxygen Treatment
- Trial of HBOT in patients with chronic Arm Lymphoedema
- Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer
- Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenographs
- Pelvic Radiation Disease Management by Hyperbaric Oxygen Therapy
- Exploiting Cancer Metabolism with Ketosis and Hyperbaric Oxygen (article)
- Hyperbaric oxygen increases glioma cell sensitivity to antitumor treatment with a novel isothiourea derivative in vitro
- Hyperbaric oxygen as an adjunctive therapy in treatment of malignancies, including brain tumours
- Further application of hyperbaric oxygen in prostate cancer
- The effect of hyperbaric oxygen on clinical outcome of patients after resection of meningiomas with conspicuous peritumoral brain edema.
- Hyperbaric oxygen treatment improved neurophysiologic performance in brain tumor patients after neurosurgery and radiotherapy
- Ketogenic diet with hyperbaric oxygen therapy for metabolic optimization and to attack cancer - video
- Starving Cancer: Dominic D’Agostino at TEDxTampaBay – video
Cardiac Disorders/Heart Disease/MI/Acute Coronary Syndrome
- Hyperbaric chamber high pressure heart surgery – infants
- Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart
- Oxygen and oxygenation in stem-cell therapy for myocardial infarction
- Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart
- Hyperbaric oxygen therapy for acute coronary syndrome
- Stem cell mobilization by hyperbaric oxygen (pdf)
- Hyperbaric oxygen therapy for treatment of neurologic sequela after atrioesophageal fistula. (pdf)
- Hyperbaric; Cardiovascular Effects
- Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart
- Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart
Cerebral Ischemia/Edema
- Hyperbaric Oxygen Reduces Blood-Brain Barrier Damage and Edema After Transient Focal Cerebral Ischemia
- Hyperbaric oxygen therapy and cerebral ischemia: neuroprotective mechanisms (abstract)
- Hyperbaric oxygen in the treatment of a radiosurgical complication: technical case report (abstract)
- Hyperbaric oxygen preconditioning reduces postoperative brain edema and improves neurological outcomes after surgical brain injury (abstract)
- Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema after LINAC radiosurgery (abstract)
- Effects of early hyperbaric oxygen therapy on clinical outcome in postoperative patients with intracranial aneurysm (abstract)
Cerebral Palsy
- Hyperbaric Oxygen Therapy in the Management of Cerebral Palsy
- Cerebral Palsy Study Dispels Inflated Costs and Biases
- Hyperbaric Oxygenation Therapy in the Treatment of Cerebral Palsy-A Review and Comparison to Currently Accepted Therapies
- Hyperbaric Oxygen Therapy (hbot) and Cerebral Palsy (cp) (video)
- Grace, a Cerebral Palsy Patient treated with Hyperbaric Oxygen Therapy at the Sahara Clinic (video)
- Cerebral Palsy Testimonial – How Stem Cells & Hyperbaric Oxygen Helped Cerebral Palsy (video)
- Causes of Cerebral Palsy Oxygen Therapy in the Neonatal Period Treatment of Cerebral Palsy with HBOT Conclusions
Colitis/Crohn’s Disease/Irritable Bowel Syndrome/Other GI Disorders
- Hyperbaric oxygen therapy stimulates colonic stem cells and induces mucosal healing in patients with refractory ulcerative colitis: a prospective case series
- Effect of hyperbaric oxygenation on normalization of intestinal function after surgical treatment of Hirschsprung disease and anorectal developmental defects in children
- Hyperbaric oxygen treatment for inflammatory bowel disease
- Effect of growth hormone, hyperbaric oxygen and combined therapy on the gastric serosa
- Hyperbaric oxygen: a novel modality to ameliorate experimental colitis
- Hyperbaric oxygen therapy for severe ulcerative colitis (abstract)
- Hyperbaric oxygen therapy is as effective as dexamethasone in the treatment of TNBS-E-induced experimental colitis (abstract)
- Efficacy of hyperbaric oxygen in patients with Crohn’s disease: two case reports (abstract)
- Crohn’s disease and hyperbaric oxygen therapy (abstract)
- A favourable response to surgical intervention and hyperbaric oxygen therapy in pyoderma gangrenosum (abstract)
- Computed tomography colonography imaging of pneumatosis intestinalis after hyperbaric oxygen therapy: a case report
- The utility of hyperbaric oxygen therapy to treat recurrent acute bowel obstruction after previous pelvic radiotherapy: a case series (abstract)
- Systematic review: The safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease. (abstract)
- Hyperbaric oxygen therapy for chronic antibiotic-refractory ischemic pouchitis.
- Adjunctive Hyperbaric Oxygen Therapy promotes successful healing in patients with refractory Crohn’s disease
- Hyperbaric oxygen in the treatment of perineal Crohn’s disease era of infliximab: a renewal interest?
- Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis
Cognitive Function
Cystitis/Other GU Disorders
- Long-term experience of hyperbaric oxygen therapy for refractory radio- or chemotherapy-induced haemorrhagic cystitis
- A cost-analysis case study of radiation cystitis treatment including hyperbaric oxygen therapy (abstract)
- Hyperbaric oxygen-A new horizon in treating cyclophosphamide-induced hemorrhagic cystitis
- Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan
- Hyperbaric oxygen treatment in radiation-induced cystitis and proctitis: a prospective cohort study on patient-perceived quality of recovery (abstract)
- Hyperbaric Oxygen for the Treatment of Interstitial Cystitis-Long-Term Results of a Prospective Pilot Study
- Safety and efficacy of hyperbaric oxygen therapy for the treatment of interstitial cystitis: a randomized, sham controlled, double-blind trial. (abstract)
- Severe cyclophosphamide-induced haemorrhagic cystitis treated with hyperbaric oxygen (abstract)
- Treatment of a radiation-induced rectal ulcer with hyperbaric oxygen therapy in a man with prostate cancer (abstract)
- Possible application of hyperbaric oxygen technology in the management of urogenital and renal diseases (abstract)
- Hyperbaric Oxygen in the Treatment of Calciphylaxis: A case series and literature review. (abstract)
- Emphysematous cystitis: Report of 2 cases with different outcomes.
- Late rectal and bladder toxicity following radiation therapy for prostate cancer: Predictive factors and treatment results.
- Healing of spongiosus-cutaneous fistula with hypebaric oxygen therapy (HBOT): a case report
- Clinical utility of hyperbaric oxygen therapy in genitourinary medicine
- Hyperbaric Oxygen Treatment of Chronic Refractory Radiation Proctitis
Dementia/Alzeimer’s Disease
- Treatment of post-anesthesia dementia with perispinal etanercept injection and hyperbaric oxygen therapy: a case report.
- Reflections on the neurotherapeutic effects of hyperbaric oxygen, Expert Review of Neurotherapeutics, Informa Healthcare
- Oxygen, a Key Factor Regulating Cell Behavior during Neurogenesis and Cerebral Diseases
- Hyperbaric oxygen therapy for vascular dementia (abstract)
- Hyperbaric oxygen therapy improves neurogenesis and brain blood supply in piriform cortex in rats with vascular dementia (abstract)
- The protective effect of hyperbaric oxygen and Ginkgo biloba extract on Aβ25-35-induced oxidative stress and neuronal apoptosis in rats (abstract)
- Hyperbaric Oxygen Therapy and Alzheimer’s Disease
- Hyperbaric oxygen therapy ameliorates pathophysiology of 3xTg-AD mouse model by attenuating neuroinflammation
- Hyperbaric oxygen therapy as a new treatment approach for Alzheimer’s disease
- Hyperbaric Oxygen Therapy Reversed Alzheimer’s (video)
- Oxygen and Pressure Epigenetics (article)
- Meta-Analysis on the Efficacy and Safey of Hyperbaric Oxygen as Adjunctive Therapy for Vascular Dementia.
- Hyperbaric Oxygen Therapy for Alzheimer’s disease
Dermatological Conditions
- Therapeutic effect of hyperbaric oxygen in psoriasis vulgaris: two case reports and a review of the literature
- A favourable response to surgical intervention and hyperbaric oxygen therapy in pyoderma gangrenosum (abstract)
- A prospective randomized controlled trial assessing the efficacy of adjunctive hyperbaric oxygen therapy in the treatment of hidradenitis suppurative. (abstract)
- Hyperbaric Oxygen Therapy for chronic ulcers in systemic sclerosis-case series
Diabetes/Diabetic Wounds
- Can major amputation rates be decreased in diabetic foot ulcers with hyperbaric oxygen therapy?
- The Efficacy Of Hyperbaric Oxygen Therapy For The Treatment Of Diabetic Autonomic Neuropathy
- IGF-1 Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers
- The role of oxygen-associated therapies for the healing of chronic wounds, particularly in patients with diabetes (abstract)
- Treatment of diabetic foot infection with hyperbaric oxygen therapy (abstract)
- Hyperbaric oxygen therapy facilitates healing of chronic foot ulcers in patients with diabetes
- Potential benefits of hyperbaric oxygen therapy on atherosclerosis and glycaemic control in patients with diabetic foot (abstract)
- Hyperbaric oxygen therapy for wound healing and limb salvage: a systematic review (abstract)
- Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers (abstract)
- Diabetic hand infections and hyperbaric oxygen therapy. (abstract)
- Hyperbaric oxygen therapy (HBOT) suppresses biomarkers of cell stress and kidney injury in diabetic mice. (abstract)
- Hyperbaric oxygen therapy reduces the risk of QTc interval prolongation in patients with diabetes and hard-to-heal foot ulcers.
- Hyperbaric Oxygen Therapy Improves Glucose Homeostasis in Type 2 Diabetes Patients: A Likely Involvement of the Carotid Bodies.
- Hyperbaric oxygen therapy increases insulin sensitivity in overweight men with and without type 2 diabetes.
- Prevention of autoimmune diabetes and induction of B-cell proliferation in NOD mice by hyperbaric oxygen therapy
- The role of hyperbaric oxygenation in the complex treatment of patients with type 1 diabetes mellitus
- Experience in the use of hyperbaric oxygenation to treat diabetes mellitus in children
- Early Effects of Hyperbaric Oxygen on Inducible Nitric Oxide Synthase Activity/Expression in Lymphocytes of Type 1 Diabetes Patients: A Prospective Pilot Study
- Neuropathy Recovery with Hyperbaric Oxygen Therapy
- The effects of hyperbaric oxygen therapy on diabetic retinopathy: A preliminary study.
- Might hyperbaric oxygen therapy (HBOT) reduce renal injury in diabetic people with diabetes mellitus? From preclinical models to human metabolomics.
Erectile Dysfunction
- The effect of hyperbaric oxygen therapy on erectile function recovery in a rat cavernous nerve injury model (abstract)
- Hyperbaric oxygen therapy for recovery of erectile function after posterior urethral reconstruction (abstract)
- Preclinical evidence for the benefits of penile rehabilitation therapy following nerve-sparing radical prostatectomy (abstract)
- The Effect of Hyperbaric Oxygen Therapy on Erectile Functions: A Prospective Clinical Study
- Hyperbaric oxygen can induce angiogenesis and recover erectile function
- The impact of hyperbaric oxygen therapy on erectile functions and serum testosterone levels in patients with erectile dysfunction.
- Reverse aging and restore blood flow - video
Eye Disorders
- Oxygen therapy in patients with retinal artery occlusion: a meta-analysis
- Hyperbaric oxygen therapy and age-related macular degeneration (abstract)
- Slowing the degenerative process, long lasting effect of hyperbaric oxygen therapy in retinitis pigmentosa (pdf)
- Retinal artery occlusion: visual outcome after treatment with hyperbaric oxygen (abstract)
- Hyperbaric oxygen therapy and the eye (abstract)
- Orbital entomophthoramycosis in an infant: recovery following surgical debridement, combination antifungal therapy and use of hyperbaric oxygen
- Hyperbaric oxygen therapy in branch retinal artery occlusion in a 15-year-old boy with methylenetetrahydrofolate reductase mutation (abstract)
- Efficacy of hyperbaric oxygen therapy in a young woman with idiopathic branch retinal artery occlusion (abstract)
- Hyperbaric oxygen for the treatment of the rare combination of central retinal vein occlusion and cilioretinal artery occlusion (abstract)
- Combined Central Retinal Artery and Vein Occlusion Associated with Factor V Leiden Mutation and Treated with Hyperbaric Oxygen (abstract)
- Reversibility of retinal ischemia due to central retinal artery occlusion by hyperbaric oxygen
- Central Retinal Artery Occlusion
- The efficacy of hyperbaric oxygen therapy in the treatment of central retinal artery occlusion
Fibromyalgia/Chronic Fatigue Syndrome
- Hyperbaric Oxygen Therapy Can Diminish Fibromyalgia Syndrome – Prospective Clinical Trial
- A new treatment modality for fibromyalgia syndrome: hyperbaric oxygen therapy. (abstract)
- A novel treatment modality for myofascial pain syndrome: hyperbaric oxygen therapy. (abstract)
- Hyperbaric oxygen therapy in chronic pain management. (abstract)
- Potential Benefits of Non-Pharmacological Therapies in Fibromyalgia
- Hyperbaric Therapy in Chronic Fatigue Syndrome (abstract)
- The efficacy of hyperbaric oxygen therapy in the management of chronic fatigue syndrome (abstract)
- Under Pressure Inc. Client Testimonials (video)
Gene Expression/Stem Cell Research/Mitochondrial Cytopathies
- The effect of bone marrow concentrate and hyperbaric oxygen therapy on bone repair.
- Hyperbaric oxygen therapy stimulates colonic stem cells and induces mucosal healing in patients with refractory ulcerative colitis: a prospective case series
- POSITIVE EFFECTS OF HYPERBARIC OXYGENATION IN CERTAIN MITROCHONDRIAL CYTOPATHIES
- Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells.
- Hyperbaric oxygen treatment induces antioxidant gene expression (abstract)
- Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart
Hearing Disorders
- Acute Tinnitus treated w/ HBOT
- Factors influencing the outcome of idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy (abstract)
- Hyperbaric oxygen therapy for acute noise-induced hearing loss: evaluation of different treatment regimens (abstract)
- The effect of hyperbaric oxygen therapy to different degree of hearing loss and types of threshold curve in sudden deafness patients (abstract)
- Hyperbaric oxygen therapy seems to enhance recovery from acute acoustic trauma (abstract)
- Hyperbaric oxygen in the treatment of sudden deafness (abstract)
- Hyperbaric oxygen therapy (HBO2) as an adjunct in the treatment of idiopathic sudden sensorineural hearing loss (ISSHL)-a case report on two patients. (abstract)
- Management of sudden hearing loss with hyperbaric oxygen therapy (abstract)
- Hyperbaric oxygen as salvage treatment for idiopathic sudden sensorineural hearing loss.
- Comparison of two different steroid treatments with hyperbaric oxygen for idiopathic sudden sensorineural hearing loss.
- The use of hyperbaric oxygen treatment for sudden sensorineural hearing loss in Europe (abstract)
- Concurrent hyperbaric oxygen therapy and intratympanic steroid application as salvage therapy after severe sudden sensorineural hearing loss (abstract)
- Hyperbaric oxygen therapy vs. medical therapy for sudden sensorineural hearing loss
Hepatitis/Liver Disorders
- Clinical pathological study of treatment of chronic hepatitis with hyperbaric oxygenation. (abstract)
- Hyperbaric oxygen therapy in parenchymal liver disease. (abstract)
- Hyperbaric oxygen therapy reduces the toll-like receptor signaling pathway in multiple organ failures. (abstract)
- Therapeutic effect of hyperbaric oxygen in hepatic artery thrombosis and functional cholestasis after orthotopic liver transplantation. (abstract)
- Beneficial effect of hyperbaric oxygenation on liver regeneration in cirrhosis. (abstract)
- Hyperbaric Oxygen Therapy in Liver Diseases
Lung Conditions
- Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients
- Hyperbaric oxygen therapy effects on pulmonary functions: a prospective cohort study
- Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms
- Are pulmonary bleb and bullae a contraindication for hyperbaric oxygen treatment?
Lyme Disease
- Lyme Disease Resources
- Biofilms: hyperbaric?
- Lyme Treatment Foundation, Inc.
- Lyme Financial Support, Education and Research Resources
- Touhed by Lyme: Resources to help you hit the ground running
- LYMEPOLICYWONK: Misdiagnosis of Lyme disease as MS -MyLymeData Quick Bytes
- Horowitz MISIDS Lyme Questionnaire
- Comparison Chart of Lyme Disease and Co-infections Symptoms
- International Lyme and Associated Diseases Society
- LymeDisease.org
- Hyperbaric Oxygenation for Lyme Vasculitis (pdf)
- Hyperbaric oxygen as a therapy of Bell’s palsy (abstract)
- Lyme disease and hyperbarics (video)
- Hyperbaric oxygen therapy as an effective adjunctive treatment for chronic Lyme disease (article)
- Under Pressure Inc. Client Testimonials (video)
- TICK TESTING
- Treatment of lyme disease with hyperbaric oxygen therapy
- Lyme disease and hyperbarics (video)
- An Overview of Lyme Disease and Hyperbaric Oxygen Therapy (article)
Miscellaneous
- Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with toxic injury due to mold exposure
- Effects of hyperbaric oxygen on aggressive periodontitis and subgingival anaerobes in Chinese patients
- Orbital entomophthoramycosis in an infant: recovery following surgical debridement, combination antifungal therapy and use of hyperbaric oxygeI
- Hyperbaric oxygen therapy in China
- Principles and practice of hyperbaric medicine: a medical practitioner’s primer
- Hyperbaric oxygen preconditioning protects skin from UV-A damage
- HBOT for Parkinson’s (video)
- HBOT and Alzheimer’s (video)
- Dr. Paul Harch Hyperbarics Inc. HBOT Treatments (video)
- Is There an Association Between Hyperbaric Oxygen Therapy and Improved Outcome of Deep Chemical Peeling? A Randomized Pilot Clinical Study
- Hyperbaric oxygen treatment induces antioxidant gene expression
Migraine/Cluster/Tension Headaches
- Hyper- or normobaric oxygen therapy to treat migraine and cluster headache pain. Cochrane review (abstract)
- Normobaric and hyperbaric oxygen therapy for migraine and cluster headache (abstract)
- Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease (abstract)
MS
- Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental traumatic brain injury in rats induces significant remyelination and a recovery of sensorimotor function.
- Long-term hyperbaric oxygenation retards progression in multiple sclerosis patients
- MS National Therapy Centres
- HBOT, Stem Cells, and Multiple Sclerosis (M.S.) (video)
- Sara’s Garden Hyperbaric Oxygen Therapy (HBOT) Testimonial – Amanda (M.S.) (video)
- HBOT AND MULTIPLE SCLEROSIS – HYPERBARIC OXYGEN THERAPY (video)
Nerve Pain/Injuries
- Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy.
- Hyperbaric oxygen treatment decreases pain in two nerve injury models (pdf)
- Effects of hyperbaric oxygen therapy on facial nerve regeneration (abstract)
- Hyperbaric oxygen as a therapy of Bell’s palsy (abstract)
- Hyperbaric Oxygen Treatment for Reflex Sympathetic Dystrophy Syndrome RSD (video)
Neuropathies
- HBOT for Neuropathy
- The effectiveness of intermittent hyperbaric oxygen in relieving drug-induced HIV-associated neuropathy.
- The Efficacy Of Hyperbaric Oxygen Therapy For The Treatment Of Diabetic Autonomic Neuropathy
- Hyperbaric oxygenation therapy alleviates chronic constrictive injury-induced neuropathic pain and reduces tumor necrosis factor-alpha production.
- Successful Treatment of Lower Limb Complex Regional Pain Syndrome
- Hyperbaric Oxygen Therapy to heal Non-Diabetic Peripheral Neuropathy – video
- Neuropathy Recovery with Hyperbaric Oxygen Therapy -video
Non-Healing Wounds and Sores
- Hyperbaric oxygen for chronic wounds (abstract)
- Hyperbaric Oxygen Therapy: Solution for Difficult to Heal Acute Wounds? Systematic Review
- Evaluation of the efficacy of hyperbaric oxygen therapy in the management of chronic nonhealing ulcer and role of periwound transcutaneous oximetry as a predictor of wound healing response: A randomized prospective controlled trial
- Improvement of ischemic non-healing wounds following hyperoxygenation: the experience at Rambam-Elisha Hyperbaric Center in Israel, 1998-2007 (abstract)
- Necrotizing fasciitis: literature review of contemporary strategies for diagnosing and management with three case reports: torso, abdominal wall, upper and lower limbs
- Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells
- The efficacy of hyperbaric oxygen therapy in improving the quality of life in patients with problem wounds (abstract)
- Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy (abstract)
- Hyperbaric Oxygen Therapy Mediates Increased Nitric Oxide Production Associated With Wound Healing: A Preliminary Study
- Hyperbaric oxygen and wound healing
- The effect of bone marrow concentrate and hyperbaric oxygen therapy on bone repair.
- Hyperbaric oxygen therapy accelerates osteoblast differentiation and promotes bone formation.
- Hyperbaric Oxygen Therapy and Wound Care (video)
- Hyperbaric Oxygen Therapy: Wound Healing & Anti-Aging – Scott Sherr (September 2014) (video)
- Necrotising soft tissue infections: the effect of hyperbaric oxygen on mortality (abstract)
Osteomyelitis
- Hyperbaric Oxygen for Osteomyelitis in a Compromised Host
- Hyperbaric oxygen therapy for wound healing and limb salvage: a systematic review (abstract)
Parkinson’s Disease
- HBOT for Parkinson’s
- Parkinson’s Case Studies HBOT
- Mild hyperbaric oxygen inhibits the decrease of dopaminergic neurons in the substantia nigra of mice with MPTP-induced Parkinson’s disease
- Hyperbaric oxygen treatment for Parkinson’s disease with severe depression and anxiety: a case report
- Hyperbaric Oxygen Therapy as Adjuvant Treatment for Hardware-Related Infections in Neuromodulation
- Parkinson’s Disease Responding To Hyperbaric Oxygen Therapy
PTSD
- Phase I Study of Low-Pressure Hyperbaric Oxygen Therapy For Blast-Induced Post-Concussion Syndrome and Post-Traumatic Stress Disorder
- Hyperbaric oxygen ameliorates worsening signs and symptoms of post-traumatic stress disorder
- More HBOT for PTSD Vets through the IHMF’s NBIRR study (video)
- U.S. Veteran Pilot Trail LSU IRB #7051 HBOT in TBI/PTSD Preliminary Data
- Dr. Paul Harch treats Iraq vets for TBI/PTSD with Hyperbaric Oxygen Therapy (HBOT), Part 1 (video)
- Dr. Paul Harch treats Iraq vets for TBI/PTSD with Hyperbaric Oxygen Therapy (HBOT), Part 2 (video)
- Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of blast-induced chronic traumatic brain injury (post-concussion syndrome) and post traumatic stress disorder: a case report
- Case Control Study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder
- A Year’s Worth of HBOT Progress (2018)
- Hyperbaric oxygen therapy restored traumatic stress-induced dysregulation of fear memory and related neurochemical abnormalities
Sepsis
Spinal Cord Injury
- Attenuating experimental spinal cord injury by hyperbaric oxygen: stimulating production of vasculoendothelial and glial cell line-derived neurotrophic growth factors and interleukin-10 (abstract)
- Hyperbaric oxygen induces endogenous neural stem cells to proliferate and differentiate in hypoxic-ischemic brain damage in neonatal rats (abstract)
- Hyperbaric oxygen therapy improves local microenvironment after spinal cord injury (abstract)
- Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Stroke/Brain Aneurysm
- The effect of hyperbaric oxygen therapy on functional impairments caused by ischemic stroke
- The efficacy of hyperbaric oxygen in hemorrhagic stroke: experimental and clinical implications
- Reflections on the neurotherapeutic effects of hyperbaric oxygen, Expert Review of Neurotherapeutics, Informa Healthcare
- Hyperbaric Oxygen Therapy for Individuals with Neurological Dysfunction
- Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients
- Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients (video)
- Decades-old stroke damage reversible with oxygen therapy, say researchers (video)
- Hyperbaric Oxygen for Cerebral Vasospasm and Brain Injury Following Subarachnoid Hemorrhage
- Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study
- Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?
- Hyperbaric oxygen for stroke treatment (editorial)
- Hyperbaric oxygen induces endogenous neural stem cells to proliferate and differentiate in hypoxic-ischemic brain damage in neonatal rats (abstract)
- Stem cell mobilization by hyperbaric oxygen (pdf)
- Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease (abstract)
- Delayed hyperbaric oxygen therapy induces cell proliferation through stabilization of cAMP responsive element binding protein in the rat model of MCAo-induced ischemic brain injury (abstract)
- Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering from anoxic brain damage.
- Recovery From Stroke with Hyperbaric Oxygen Therapy (HBOT) (video)
- Stroke And Hyperbaric Chambers (video)
- A Dual Role for Hyperbaric Oxygen in Stroke Neuroprotection: Preconditioning of the Brain and Stem Cells
Surgical Sites with Grafts or Flaps
- Does hyperbaric oxygen administration before or after irradiation decrease side effects of irradiation on implant sites? (abstract)
- The effect of hyperbaric oxygen on compromised grafts and flaps (abstract)
- Evaluation of hyperbaric oxygen therapy for free flaps using planar optical oxygen sensors. Preliminary results (abstract)
- The influence of hyperbaric oxygen treatment on the healing of experimental defects filled with different bone graft substitutes
- Fasciotomy closure using simultaneous vacuum-assisted closure and hyperbaric oxygen (abstract)
- Is Tracheal Transplantation Possible With Cryopreserved Tracheal Allograft and Hyperbaric Oxygen Therapy? An Experimental Study.
- The Science of Hyperbaric Oxygen for Flaps and Grafts (abstract)
Surgery (pre & post) Orthopedic/Plastic/Reconstruction/Resection/Stereotactic Radiosurgery
- Hyperbaric oxygen preconditioning protects skin from UV-A damage (abstract)
- Safety and efficacy of early postoperative hyperbaric oxygen therapy with restriction of transfusions in patients with HCC who have undergone partial hepatectomy (abstract)
- Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells
- Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds (abstract)
- Prevention of avascular necrosis in displaced talar neck fractures by hyperbaric oxygenation therapy: a dual case report (abstract)
- Stem cell mobilization by hyperbaric oxygen (pdf)
- Hyperbaric oxygen therapy and liver transplantation (abstract)
- Hyperbaric oxygen in the treatment of a radiosurgical complication: technical case report (abstract)
- Hyperbaric oxygen therapy for treatment of adverse radiation effects after stereotactic radiosurgery of arteriovenous malformations: case report and review of literature (abstract)
- Hyperbaric oxygen preconditioning reduces postoperative brain edema and improves neurological outcomes after surgical brain injury (abstract)
- Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema after LINAC radiosurgery (abstract)
- Hyperbaric oxygen therapy facilitates surgery on complex open elbow injuries: preliminary results (abstract)
- Hyperbaric oxygen in the treatment of postoperative infections in paediatric patients with neuromuscular spine deformity
- Hyperbaric oxygen and wound healing
- Hyperbaric Oxygen Preconditioning-Induced Neuroprotection Against Ischemic Stroke
- Does hyperbaric oxygen therapy prevent airway anastomosis from breakdown?
- Efficiency of Hyperbaric Oxygen Therapy in Iatrogenic Spinal Infections (abstract)
- Hyperbaric oxygen therapy as an alternative to surgery for non-healing pharyngocutaneous fistula (abstract)
- Can hyperbaric oxygen be used to prevent deep infections in neuro-muscular scoliosis surgery?
- Hyperbaric Oxygen Therapy as Adjuvant Treatment for Hardware-Related Infections in Neuromodulation
- Hyperbaric Oxygen Therapy: An Effective and Noninvasive Therapy for Complications of Ear Reconstruction.
Traumatic/Chronic Brain/Head Injury
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- Phase I Study of Low-Pressure Hyperbaric Oxygen Therapy For Blast-Induced Post-Concussion Syndrome and Post-Traumatic Stress Disorder
- Hyperbaric oxygen: B-level evidence in mild traumatic brain injury clinical trials.
- Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental traumatic brain injury in rats induces significant remyelination and a recovery of sensorimotor function.
- Hyperbaric oxygen therapy and cerebral ischemia: neuroprotective mechanisms
- Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with toxic injury due to mold exposure
- A Year’s Worth of HBOT Progress (2018)
- Effect of hyperbaric oxygen therapy on chronic neurocognitive de cits of post- traumatic brain injury patients: retrospective analysis
- Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder
- Reflections on the neurotherapeutic effects of hyperbaric oxygen, Expert Review of Neurotherapeutics, Informa Healthcare
- Hyperbaric oxygen therapy ameliorates local brain metabolism, brain edema and inflammatory response
- Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury – Randomized Prospective Trial
- Hyperbaric Oxygen Therapy for Individuals with Neurological Dysfunction
- Role of hyperbaric oxygen therapy in severe head injury in children
- Hyperbaric oxygen therapy for traumatic brain injury
- Hyperbaric Oxygen Treatment (HBOT) for TBI/PTS (video)
- Improving neuropsychological function after chronic brain injury with hyperbaric oxygen (abstract)
- Use of hyperbaric oxygen in traumatic brain injury: Retrospective analysis of data of 20 patients treated at a tertiary care centre (abstract)
- Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports
- Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of mitochondrial membrane properties (abstract)
- Improvement of attention span and reaction time with hyperbaric oxygen treatment in patients with toxic injury due to mold exposure
- Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?
- Hyperbaric Oxygen Therapy for Reduction of Secondary Brain Damage in Head Injury: An Animal Model of Brain Contusion
- Hyperbaric oxygen induces endogenous neural stem cells to proliferate and differentiate in hypoxic-ischemic brain damage in neonatal rats (abstract)
- U.S. Veteran Pilot Trail LSU IRB #7051 HBOT in TBI/PTSD Preliminary Data
- Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease (abstract)
- Delayed hyperbaric oxygen therapy induces cell proliferation through stabilization of cAMP responsive element binding protein in the rat model of MCAo-induced ischemic brain injury (abstract)
- Microglial activation induced by traumatic brain injury is suppressed by postinjury treatment with hyperbaric oxygen therapy (abstract)
- Dr. Paul Harch treats Iraq vets for TBI/PTSD with Hyperbaric Oxygen Therapy (HBOT), Part 1 (video)
- Dr. Paul Harch treats Iraq vets for TBI/PTSD with Hyperbaric Oxygen Therapy (HBOT), Part 2 (video)
- Overcoming Brain Injury – Juan’s Story (video)
- Sara’s Garden Hyperbaric Oxygen Therapy (HBOT) Testimonial – Aubree (TBI) (video)
- Hyperbaric Oxygen Therapy-Bryan Murphy (video)
- The Courage to Come Back: A story of hope. (video)
- Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury.
- Clinical results in brain injury trials using HBO2 therapy: Another perspective.
- Hyperbaric Oxygen in Mild TBI: Conflicting Civilian and Department of Defense Studies Explained.
- Clinical research on postoperative efficacy and related factors of early simulation hyperbaric oxygen therapy for severe craniocerebral injury (abstract)
- Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury (abstract)
- Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering from anoxic brain damage.
- Hyperbaric oxygen in chronic traumatic brain injury: oxygen, pressure, and gene therapy.
- Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental traumatic brain injury
- Hyperbaric Oxygen Therapy Can Induce Angiogenesis and Regeneration of Nerve Fibers in Traumatic Brain Injury Patients
- Case Control Study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder
- HBOT for TBI in Israel (article)
- The National Brain Injury Rescue and Rehabilitation Study – a multicenter observational study of hyperbaric oxygen for mild traumatic brain injury with post-concussive symptoms.
- Hyperbaric oxygen increases glioma cell sensitivity to antitumor treatment with a novel isothiourea derivative in vitro
- Hyperbaric oxygen as an adjunctive therapy in treatment of malignancies, including brain tumours
- Joe Namath on using a hyperbaric chamber to treat concussion affects
- Football players and their hyperbaric chambers – video